Universal Donor Cells Universal Cells has created a suite of tools to generate Universal Donor Cells to be used in allogeneic transplantation without the need for HLA matching. Read More
Single Chain HLA Vectors Universal Donor Cells don't express any HLA class I alleles, and can be further engineered to express customized class I genes as single chain fusion proteins. For example, cells that express the non-polymorphic HLA-E protein will resist lysis by Natural Killer cells. Read More
Custom Genome Editing We enable our customers to access full control of the stem cell genome by providing custom rAAV vectors optimized for pluripotent stem cell delivery. Read More

Welcome to Universal Cells, Inc.!

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Universal Cells aims to provide our customers with the tools they need to reliably and accurately edit the stem cell genome.  Our technology is based on AAV-mediated gene targeting, which offers high accuracy and safety, and the best vehicle available for cellular delivery.  

 

A major focus of Universal Cells is the genetic manipulation of histocompatibility genes in order to create non-immunogenic therapeutic stem cell lines. We have developed proprietary technology that enables the immune evasion of transplantable stem cells by eliminating and/or customizing HLA gene expression, thus allowing researchers and companies to work with a histocompatible, allogeneic, off-the-shelf stem cell product for the regenerative medicine market.